Version 5.4
Homo sapiens Protein: FCHO2
Summary
InnateDB Protein IDBP-479422.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FCHO2
Protein Name FCH domain only 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000427296
InnateDB Gene IDBG-27912 (FCHO2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001786 phosphatidylserine binding
GO:0005515 protein binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0035091 phosphatidylinositol binding
Biological Process
GO:0010324 membrane invagination
GO:0048268 clathrin coat assembly
GO:0072583 clathrin-mediated endocytosis
GO:0072659 protein localization to plasma membrane
Cellular Component
GO:0005886 plasma membrane
GO:0005905 coated pit
GO:0030136 clathrin-coated vesicle
Protein Structure and Domains
PDB ID
InterPro IPR001060 FCH domain
IPR018808 Muniscin C-terminal
PFAM PF00611
PF10291
PRINTS
PIRSF
SMART SM00055
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q0JRZ9
PhosphoSite PhosphoSite-Q0JRZ9
TrEMBL B4DEU7
UniProt Splice Variant
Entrez Gene 115548
UniGene Hs.741336
RefSeq NP_001139504
HUGO HGNC:25180
OMIM 613438
CCDS CCDS54868
HPRD 13319
IMGT
EMBL AC008972 AC020893 AC020942 AK291782 AK293796 AK295141 AL831971 BC014311 BC137070
GenPept AAH14311 AAI37071 BAF84471 BAG57208 BAG58162

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca