InnateDB Protein
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IDBP-479676.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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DIMT1
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Protein Name
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DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000421754
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InnateDB Gene
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IDBG-23321 (DIMT1)
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Protein Structure
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Function |
Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle. {ECO:0000250}.
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Subcellular Localization |
Nucleus, nucleolus {ECO:0000269PubMed:12429849}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 34 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
34
[view]
|
Protein-Protein |
34
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0000179
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rRNA (adenine-N6,N6-)-dimethyltransferase activity
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GO:0008649
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rRNA methyltransferase activity
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GO:0016433
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rRNA (adenine) methyltransferase activity
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GO:0044822
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poly(A) RNA binding
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GO:0052909
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18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001737
Ribosomal RNA adenine methylase transferase
IPR011530
Ribosomal RNA adenine dimethylase
IPR020598
Ribosomal RNA adenine methylase transferase, N-terminal
IPR029063
S-adenosyl-L-methionine-dependent methyltransferase-like
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PFAM |
PF00398
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PRINTS |
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PIRSF |
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SMART |
SM00650
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TIGRFAMs |
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Modification |
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SwissProt |
Q9UNQ2
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PhosphoSite |
PhosphoSite-Q9UNQ2
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TrEMBL |
B4DRY2
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UniProt Splice Variant |
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Entrez Gene |
27292
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UniGene |
Hs.733849
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RefSeq |
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HUGO |
HGNC:30217
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OMIM |
612499
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CCDS |
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HPRD |
13676
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IMGT |
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EMBL |
AF091078
AF102147
AJ009761
AK299480
BC002841
BC010874
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GenPept |
AAC72947
AAC97955
AAH02841
AAH10874
BAG61444
CAA08815
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