InnateDB Protein
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IDBP-479688.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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EPGN
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Protein Name
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epithelial mitogen homolog (mouse)
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000424392
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InnateDB Gene
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IDBG-24347 (EPGN)
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Protein Structure
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Function |
Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases. {ECO:0000269PubMed:15611079}.
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Subcellular Localization |
Isoform 1: Membrane {ECO:0000305}; Single- pass type I membrane protein {ECO:0000305}.Isoform 2: Membrane {ECO:0000305}; Single- pass type I membrane protein {ECO:0000305}.Isoform 3: Secreted {ECO:0000305}.Isoform 4: Secreted {ECO:0000305}.Isoform 5: Secreted {ECO:0000305}.Isoform 6: Secreted {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
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Biological Process |
GO:0000187
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activation of MAPK activity
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GO:0001525
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angiogenesis
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GO:0008284
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positive regulation of cell proliferation
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GO:0043406
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positive regulation of MAP kinase activity
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GO:0045741
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positive regulation of epidermal growth factor-activated receptor activity
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GO:0045840
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positive regulation of mitosis
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GO:0050679
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positive regulation of epithelial cell proliferation
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Cellular Component |
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PDB ID |
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q6UW88
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
255324
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UniGene |
Hs.401237
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RefSeq |
NP_001257922
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HUGO |
HGNC:17470
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OMIM |
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CCDS |
CCDS59476
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HPRD |
10866
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IMGT |
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EMBL |
AK289455
AY358920
DQ235264
DQ235265
DQ235266
DQ235267
DQ235268
DQ235269
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GenPept |
AAQ89279
ABB60043
ABB60044
ABB60045
ABB60046
ABB60047
ABB60048
BAF82144
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