InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SEC62

Summary

InnateDB Protein

IDBP-480200.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SEC62

Protein Name

SEC62 homolog (S. cerevisiae)

Synonyms

Dtrp1; HTP1; TLOC1; TP-1;

Species

Homo sapiens

Ensembl Protein

ENSP00000420331

InnateDB Gene

IDBG-64313 (SEC62)

Protein Structure

UniProt Annotation

Function

Required for preprotein translocation. {ECO:0000250}.

Subcellular Localization

Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004872	receptor activity
GO:0005524	ATP binding
GO:0008565	protein transporter activity
GO:0042626	ATPase activity, coupled to transmembrane movement of substances

Biological Process

GO:0006613	cotranslational protein targeting to membrane
GO:0006620	posttranslational protein targeting to membrane
GO:0006810	transport
GO:0015031	protein transport
GO:0055085	transmembrane transport

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0005791	rough endoplasmic reticulum
GO:0016020	membrane
GO:0016021	integral component of membrane