InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PPP3CA

Summary

InnateDB Protein

IDBP-481743.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PPP3CA

Protein Name

protein phosphatase 3, catalytic subunit, alpha isozyme

Synonyms

CALN; CALNA; CALNA1; CCN1; CNA1; PPP2B;

Species

Homo sapiens

Ensembl Protein

ENSP00000422781

InnateDB Gene

IDBG-31818 (PPP3CA)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 66 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Experimentally validated
Total	66 [view]
Protein-Protein	64 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004722	protein serine/threonine phosphatase activity
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0005516	calmodulin binding
GO:0008144	drug binding
GO:0019899	enzyme binding
GO:0033192	calmodulin-dependent protein phosphatase activity
GO:0046983	protein dimerization activity

Biological Process

GO:0006470	protein dephosphorylation
GO:0016311	dephosphorylation
GO:0035690	cellular response to drug
GO:0038095	Fc-epsilon receptor signaling pathway
GO:0042110	T cell activation
GO:0045087	innate immune response (InnateDB)
GO:0051592	response to calcium ion