Version 5.4
Homo sapiens Protein: BIN3
Summary
InnateDB Protein IDBP-481811.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BIN3
Protein Name bridging integrator 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000430423
InnateDB Gene IDBG-11206 (BIN3)
Protein Structure
UniProt Annotation
Function Involved in cytokinesis and septation where it has a role in the localization of F-actin.
Subcellular Localization Cytoplasm, cytoskeleton.
Disease Associations
Tissue Specificity Ubiquitously expressed except in brain. {ECO:0000269PubMed:11274158}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008093 cytoskeletal adaptor activity
Biological Process
GO:0000910 cytokinesis
GO:0000917 barrier septum assembly
GO:0007015 actin filament organization
GO:0008104 protein localization
GO:0009826 unidimensional cell growth
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
Protein Structure and Domains
PDB ID
InterPro IPR004148 BAR domain
IPR015404 Vps5 C-terminal
PFAM PF03114
PF09325
PRINTS
PIRSF
SMART SM00721
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NQY0
PhosphoSite PhosphoSite-Q9NQY0
TrEMBL
UniProt Splice Variant
Entrez Gene 55909
UniGene Hs.654720
RefSeq
HUGO HGNC:1054
OMIM 606396
CCDS
HPRD 05904
IMGT
EMBL AF271732 AK001289 AK023980 BC001223 BC009824
GenPept AAF76218 AAH01223 AAH09824 BAA91603 BAB14751

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca