Version 5.4
Homo sapiens Protein: SSBP1
Summary
InnateDB Protein IDBP-481940.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SSBP1
Protein Name single-stranded DNA binding protein 1
Synonyms Mt-SSB; mtSSB; SOSS-B1; SSBP;
Species Homo sapiens
Ensembl Protein ENSP00000419665
InnateDB Gene IDBG-44535 (SSBP1)
Protein Structure
UniProt Annotation
Function This protein binds preferentially and cooperatively to ss-DNA. Probably involved in mitochondrial DNA replication. Associates with mitochondrial DNA.
Subcellular Localization Mitochondrion {ECO:0000269PubMed:18063578}. Mitochondrion matrix, mitochondrion nucleoid {ECO:0000269PubMed:18063578}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 91 experimentally validated interaction(s) in this database.
Experimentally validated
Total 91 [view]
Protein-Protein 90 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003682 chromatin binding
GO:0003697 single-stranded DNA binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006260 DNA replication
GO:0051096 positive regulation of helicase activity
GO:0070584 mitochondrion morphogenesis
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0042645 mitochondrial nucleoid
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000424 Primosome PriB/single-strand DNA-binding
IPR011344 Single-stranded DNA-binding protein
IPR012340 Nucleic acid-binding, OB-fold
PFAM PF00436
PRINTS
PIRSF PIRSF002070
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q04837
PhosphoSite PhosphoSite-Q04837
TrEMBL E7EUY5
UniProt Splice Variant
Entrez Gene 6742
UniGene Hs.740496
RefSeq NP_001243439
HUGO HGNC:11317
OMIM 600439
CCDS CCDS5866
HPRD 02703
IMGT
EMBL AC004918 AC004979 AF277319 AK313033 BC000895 CH236950 CH471070 HQ206146 HQ206147 HQ206148 HQ206149 HQ206150 HQ206151 HQ206152 HQ206153 HQ206154 HQ206155 HQ206156 HQ206157 HQ206158 HQ206159 HQ206160 HQ206161 HQ206162 HQ206163 HQ206164 HQ206165 HQ206166 HQ206167 HQ206168 HQ206169 HQ206170 HQ206171 HQ206172 HQ206173 HQ206174 HQ206175 HQ206176 HQ206177 HQ206178 HQ206179 HQ206180 HQ206181 HQ206182 HQ206183 HQ206184 HQ206185 M94556
GenPept AAA36332 AAH00895 AAK69112 ADP92054 ADP92055 ADP92056 ADP92057 ADP92058 ADP92059 ADP92060 ADP92061 ADP92062 ADP92063 ADP92064 ADP92065 ADP92066 ADP92067 ADP92068 ADP92069 ADP92070 ADP92071 ADP92072 ADP92073 ADP92074 ADP92075 ADP92076 ADP92077 ADP92078 ADP92079 ADP92080 ADP92081 ADP92082 ADP92083 ADP92084 ADP92085 ADP92086 ADP92087 ADP92088 ADP92089 ADP92090 ADP92091 ADP92092 ADP92093 BAG35866 EAL24018 EAW83978 EAW83981

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca