Version 5.4
Homo sapiens Protein: SRP19
Summary
InnateDB Protein IDBP-481948.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SRP19
Protein Name signal recognition particle 19kDa
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000424870
InnateDB Gene IDBG-37104 (SRP19)
Protein Structure
UniProt Annotation
Function Signal-recognition-particle assembly, binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
Subcellular Localization Cytoplasm.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
Experimentally validated
Total 22 [view]
Protein-Protein 21 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008312 7S RNA binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006412 translation
GO:0006613 cotranslational protein targeting to membrane
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
GO:0010467 gene expression
GO:0042493 response to drug
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005786 signal recognition particle, endoplasmic reticulum targeting
GO:0005829 cytosol
GO:0048500 signal recognition particle
Protein Structure and Domains
PDB ID
InterPro IPR002778 Signal recognition particle, SRP19 subunit
PFAM PF01922
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P09132
PhosphoSite PhosphoSite-P09132
TrEMBL
UniProt Splice Variant
Entrez Gene 6728
UniGene Hs.637001
RefSeq NP_003126
HUGO HGNC:11300
OMIM 182175
CCDS CCDS4108
HPRD 01644
IMGT
EMBL AC008536 AC008575 AK311803 BC010947 BC017830 BU661702 CH471086 X12791
GenPept AAH10947 AAH17830 BAG34746 CAA31280 EAW48999 EAW49000

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca