Version 5.4
Homo sapiens Protein: NUDT9
Summary
InnateDB Protein IDBP-481972.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NUDT9
Protein Name nudix (nucleoside diphosphate linked moiety X)-type motif 9
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000421811
InnateDB Gene IDBG-29004 (NUDT9)
Protein Structure
UniProt Annotation
Function Hydrolyzes ADP-ribose (ADPR) to AMP and ribose 5'- phosphate.
Subcellular Localization Isoform 1: Mitochondrion.
Disease Associations
Tissue Specificity Ubiquitously expressed but isoform 1 is the most predominant isoform. {ECO:0000269PubMed:12427752}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016787 hydrolase activity
GO:0019144 ADP-sugar diphosphatase activity
GO:0047631 ADP-ribose diphosphatase activity
Biological Process
GO:0034656 nucleobase-containing small molecule catabolic process
GO:0044281 small molecule metabolic process
GO:0055086 nucleobase-containing small molecule metabolic process
Cellular Component
GO:0005622 intracellular
GO:0005759 mitochondrial matrix
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000086 NUDIX hydrolase domain
IPR015797 NUDIX hydrolase domain-like
PFAM PF00293
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BW91
PhosphoSite PhosphoSite-Q9BW91
TrEMBL D6RAW2
UniProt Splice Variant
Entrez Gene 53343
UniGene Hs.149500
RefSeq NP_932155
HUGO HGNC:8056
OMIM 606022
CCDS CCDS3621
HPRD 09353
IMGT
EMBL AC112250 AF273028 AK074845 AK075408 AY026252 AY359123 BC000542
GenPept AAH00542 AAK07671 AAM46068 AAQ89480 BAC11239 BAC11601

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca