Version 5.4
Homo sapiens Protein: ITGA2
Summary
InnateDB Protein IDBP-482017.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ITGA2
Protein Name integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
Synonyms BR; CD49B; GPIa; HPA-5; VLA-2; VLAA2;
Species Homo sapiens
Ensembl Protein ENSP00000424642
InnateDB Gene IDBG-20326 (ITGA2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 33 experimentally validated interaction(s) in this database.
Experimentally validated
Total 33 [view]
Protein-Protein 31 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007155 cell adhesion
GO:0007229 integrin-mediated signaling pathway
Cellular Component
GO:0008305 integrin complex
Protein Structure and Domains
PDB ID
InterPro IPR000413 Integrin alpha chain
IPR002035 von Willebrand factor, type A
IPR013517 FG-GAP repeat
IPR013519 Integrin alpha beta-propellor
PFAM PF00092
PF01839
PF14312
PRINTS PR01185
PIRSF
SMART SM00327
SM00191
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q71V33
UniProt Splice Variant
Entrez Gene 3673
UniGene
RefSeq
HUGO HGNC:6137
OMIM 192974
CCDS
HPRD 01893
IMGT
EMBL AC008966 AF035968 HQ202727
GenPept AAC94975 ADZ28533

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca