Version 5.4
Homo sapiens Protein: HGD
Summary
InnateDB Protein IDBP-482659.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HGD
Protein Name homogentisate 1,2-dioxygenase
Synonyms AKU; HGO;
Species Homo sapiens
Ensembl Protein ENSP00000419838
InnateDB Gene IDBG-51830 (HGD)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 9 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004411 homogentisate 1,2-dioxygenase activity
Biological Process
GO:0006559 L-phenylalanine catabolic process
GO:0006570 tyrosine metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR005708 Homogentisate 1,2-dioxygenase
IPR011051 RmlC-like cupin domain
PFAM PF04209
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H7C5G7
UniProt Splice Variant
Entrez Gene 3081
UniGene Hs.368254
RefSeq
HUGO HGNC:4892
OMIM 607474
CCDS
HPRD 06315
IMGT
EMBL AC126182 AC133474
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca