Version 5.4
Homo sapiens Protein: AR
Summary
InnateDB Protein IDBP-482695.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AR
Protein Name androgen receptor
Synonyms AIS; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM;
Species Homo sapiens
Ensembl Protein ENSP00000421155
InnateDB Gene IDBG-73722 (AR)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 453 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated
Total 453 [view]
Protein-Protein 433 [view]
Protein-DNA 15 [view]
Protein-RNA 0
DNA-DNA 5 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0004882 androgen receptor activity
GO:0005496 steroid binding
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0030521 androgen receptor signaling pathway
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001103 Androgen receptor
IPR001628 Zinc finger, nuclear hormone receptor-type
PFAM PF02166
PF00105
PRINTS PR00521
PR00047
PIRSF
SMART SM00399
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q9NUA2
UniProt Splice Variant
Entrez Gene 367
UniGene Hs.76704
RefSeq
HUGO HGNC:644
OMIM 313700
CCDS
HPRD 02437
IMGT
EMBL AF321915 AF321917 AL049564 AL158016 AL356358
GenPept AAK09424 AAK09426

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca