InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RGS14

Summary

InnateDB Protein

IDBP-482808.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RGS14

Protein Name

regulator of G-protein signaling 14

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000422329

InnateDB Gene

IDBG-59816 (RGS14)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	23 [view]
Protein-Protein	22 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005057	receptor signaling protein activity
GO:0030695	GTPase regulator activity

Biological Process

GO:0007165	signal transduction
GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
GO:0038032	termination of G-protein coupled receptor signaling pathway

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000342 Regulator of G protein signalling domain
IPR003109 GoLoco motif
IPR003116 Raf-like Ras-binding
IPR016137 Regulator of G protein signalling superfamily
IPR029071 Ubiquitin-related domain

PFAM

PF00615
PF02188
PF02196

PRINTS

PR01301

PIRSF

SMART

SM00390
SM00455
SM00315

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt