InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ABP1

Summary

InnateDB Protein

IDBP-48287.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ABP1

Protein Name

amiloride binding protein 1 (amine oxidase (copper-containing))

Synonyms

ABP; ABP1; DAO; DAO1; KAO;

Species

Homo sapiens

Ensembl Protein

ENSP00000354193

InnateDB Gene

IDBG-48285 (ABP1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004872	receptor activity
GO:0005261	cation channel activity
GO:0005272	sodium channel activity
GO:0005507	copper ion binding
GO:0005509	calcium ion binding
GO:0008131	primary amine oxidase activity
GO:0008144	drug binding
GO:0008201	heparin binding
GO:0008270	zinc ion binding
GO:0032403	protein complex binding
GO:0042803	protein homodimerization activity
GO:0048038	quinone binding
GO:0052597	diamine oxidase activity
GO:0052598	histamine oxidase activity
GO:0052599	methylputrescine oxidase activity
GO:0052600	propane-1,3-diamine oxidase activity

Biological Process

GO:0009308	amine metabolic process
GO:0035725	sodium ion transmembrane transport
GO:0035874	cellular response to copper ion starvation
GO:0042493	response to drug
GO:0046677	response to antibiotic
GO:0055114	oxidation-reduction process
GO:0071280	cellular response to copper ion
GO:0071420	cellular response to histamine
GO:0071504	cellular response to heparin
GO:0097185	cellular response to azide

Cellular Component

GO:0005615	extracellular space
GO:0005777	peroxisome
GO:0005886	plasma membrane
GO:0005923	tight junction
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000269 Copper amine oxidase
IPR015798 Copper amine oxidase, C-terminal
IPR015800 Copper amine oxidase, N2-terminal
IPR015802 Copper amine oxidase, N3-terminal
IPR016182 Copper amine oxidase, N-terminal

PFAM

PF01179
PF02727
PF02728

PRINTS

PR00766

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P19801