Version 5.4
Homo sapiens Protein: DKK2
Summary
InnateDB Protein IDBP-483432.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DKK2
Protein Name dickkopf homolog 2 (Xenopus laevis)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000423797
InnateDB Gene IDBG-33265 (DKK2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0008270 zinc ion binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0007275 multicellular organismal development
GO:0030178 negative regulation of Wnt signaling pathway
Cellular Component
GO:0005576 extracellular region
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001138 Zn(2)-C6 fungal-type DNA-binding domain
IPR006796 Dickkopf, N-terminal cysteine-rich
PFAM PF00172
PF04706
PRINTS
PIRSF
SMART SM00066
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D6RGF1
UniProt Splice Variant
Entrez Gene 27123
UniGene Hs.581804
RefSeq
HUGO HGNC:2892
OMIM 605415
CCDS
HPRD 05658
IMGT
EMBL AC003099 AC104663 AC106863 AP001819
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca