Version 5.4
Homo sapiens Protein: MCM2
Summary
InnateDB Protein IDBP-483867.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MCM2
Protein Name minichromosome maintenance complex component 2
Synonyms BM28; CCNL1; cdc19; CDCL1; D3S3194; MITOTIN;
Species Homo sapiens
Ensembl Protein ENSP00000419802
InnateDB Gene IDBG-54871 (MCM2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 126 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 126 [view]
Protein-Protein 123 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0005524 ATP binding
Biological Process
GO:0006270 DNA replication initiation
Cellular Component
GO:0005634 nucleus
GO:0042555 MCM complex
Protein Structure and Domains
PDB ID
InterPro IPR008045 DNA replication licensing factor Mcm2
PFAM PF12619
PRINTS PR01658
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL C9JZ21
UniProt Splice Variant
Entrez Gene 4171
UniGene Hs.477481
RefSeq
HUGO HGNC:6944
OMIM 116945
CCDS
HPRD 00303
IMGT
EMBL AC023593
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca