Version 5.4
Homo sapiens Protein: TNKS
Summary
InnateDB Protein IDBP-483929.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TNKS
Protein Name tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
Synonyms ARTD5; PARP-5a; PARP5A; PARPL; pART5; TIN1; TINF1; TNKS1;
Species Homo sapiens
Ensembl Protein ENSP00000430920
InnateDB Gene IDBG-6906 (TNKS)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 38 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 38 [view]
Protein-Protein 38 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003950 NAD+ ADP-ribosyltransferase activity
Biological Process
GO:0008152 metabolic process
GO:0016055 Wnt signaling pathway
GO:0032212 positive regulation of telomere maintenance via telomerase
GO:0051225 spindle assembly
Cellular Component
GO:0005634 nucleus
GO:0031965 nuclear membrane
Protein Structure and Domains
PDB ID
InterPro IPR020683 Ankyrin repeat-containing domain
PFAM PF11929
PF12796
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E5RHD2
UniProt Splice Variant
Entrez Gene 8658
UniGene Hs.711310
RefSeq
HUGO HGNC:11941
OMIM 603303
CCDS
HPRD 04490
IMGT
EMBL AC021242 AC103834 AC103877 AC104052
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca