Version 5.4
Homo sapiens Protein: PFN2
Summary
InnateDB Protein IDBP-484165.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PFN2
Protein Name profilin 2
Synonyms D3S1319E; PFL;
Species Homo sapiens
Ensembl Protein ENSP00000418521
InnateDB Gene IDBG-60946 (PFN2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 39 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 39 [view]
Protein-Protein 39 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
Biological Process
GO:0030036 actin cytoskeleton organization
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR005454 Profilin, chordates
IPR005455 Profilin
PFAM PF00235
PRINTS PR01639
PR00392
PR01640
PIRSF
SMART SM00392
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F2Z3G0
UniProt Splice Variant
Entrez Gene 5217
UniGene Hs.91747
RefSeq
HUGO HGNC:8882
OMIM 176590
CCDS
HPRD 01451
IMGT
EMBL AC022494 AC117395
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca