Version 5.4
Homo sapiens Protein: PDPN
Summary
InnateDB Protein IDBP-484192.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PDPN
Protein Name podoplanin
Synonyms AGGRUS; GP36; Gp38; GP40; HT1A-1; OTS8; PA2.26; T1A; T1A-2; T1A2; TI1A;
Species Homo sapiens
Ensembl Protein ENSP00000425304
InnateDB Gene IDBG-90582 (PDPN)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0000902 cell morphogenesis
GO:0001946 lymphangiogenesis
GO:0008360 regulation of cell shape
GO:0030324 lung development
GO:0051272 positive regulation of cellular component movement
Cellular Component
GO:0001726 ruffle
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
GO:0030027 lamellipodium
GO:0030175 filopodium
GO:0031258 lamellipodium membrane
GO:0031527 filopodium membrane
GO:0031528 microvillus membrane
GO:0032587 ruffle membrane
Protein Structure and Domains
PDB ID
InterPro IPR008783 Podoplanin
PFAM PF05808
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q86YL7
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 10630
UniGene Hs.468675
RefSeq
HUGO HGNC:29602
OMIM 608863
CCDS CCDS44060
HPRD 16398
IMGT
EMBL AB127958 AF030427 AF030428 AF390106 AJ225022 AK075327 AK075345 AK312607 AL354712 AL359771 AY194238 BC014668 BC022812
GenPept AAD01899 AAD01900 AAH14668 AAH22812 AAM73655 AAO22143 BAC11550 BAC11557 BAD04046 BAG35495 CAA12352 CAI17983 CAI17984

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca