InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RASA1

Summary

InnateDB Protein

IDBP-484627.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RASA1

Protein Name

RAS p21 protein activator (GTPase activating protein) 1

Synonyms

CM-AVM; CMAVM; GAP; p120GAP; p120RASGAP; PKWS; RASA; RASGAP;

Species

Homo sapiens

Ensembl Protein

ENSP00000420905

InnateDB Gene

IDBG-32785 (RASA1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 103 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	103 [view]
Protein-Protein	100 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	2 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005096	GTPase activator activity
GO:0005515	protein binding

Biological Process

GO:0007165	signal transduction
GO:0043547	positive regulation of GTPase activity
GO:0051056	regulation of small GTPase mediated signal transduction

Cellular Component

GO:0005622

intracellular

Protein Structure and Domains

PDB ID

InterPro

IPR000008 C2 domain
IPR000980 SH2 domain
IPR001452 SH3 domain
IPR001849 Pleckstrin homology domain
IPR001936 Ras GTPase-activating protein
IPR008936 Rho GTPase activation protein

PFAM