Version 5.4
Homo sapiens Protein: EIF4E
Summary
InnateDB Protein IDBP-484928.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EIF4E
Protein Name eukaryotic translation initiation factor 4E
Synonyms AUTS19; CBP; EIF4E1; EIF4EL1; EIF4F;
Species Homo sapiens
Ensembl Protein ENSP00000423977
InnateDB Gene IDBG-30970 (EIF4E)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 96 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated
Total 96 [view]
Protein-Protein 91 [view]
Protein-DNA 2 [view]
Protein-RNA 2 [view]
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
Biological Process
GO:0006413 translational initiation
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR001040 Translation Initiation factor eIF- 4e
IPR023398 Translation Initiation factor eIF- 4e-like domain
PFAM PF01652
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D6RBW1
UniProt Splice Variant
Entrez Gene 1977
UniGene Hs.596163
RefSeq XP_006714189
HUGO HGNC:3287
OMIM 133440
CCDS
HPRD 00591
IMGT
EMBL AC019131 AC093836
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca