InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RUVBL1

Summary

InnateDB Protein

IDBP-485369.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RUVBL1

Protein Name

RuvB-like 1 (E. coli)

Synonyms

ECP54; INO80H; NMP238; PONTIN; Pontin52; RVB1; TIH1; TIP49; TIP49A;

Species

Homo sapiens

Ensembl Protein

ENSP00000417254

InnateDB Gene

IDBG-55108 (RUVBL1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 207 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	208 [view]
Protein-Protein	205 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003678	DNA helicase activity
GO:0005524	ATP binding
GO:0009378	four-way junction helicase activity
GO:0043141	ATP-dependent 5'-3' DNA helicase activity

Biological Process

GO:0006281	DNA repair
GO:0006310	DNA recombination
GO:0032508	DNA duplex unwinding

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR008824 DNA helicase, Holliday junction RuvB type, N-terminal
IPR010339 TIP49, C-terminal
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF05496
PF06068

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-