InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: LGALS4

Summary

InnateDB Protein

IDBP-49544.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

LGALS4

Protein Name

lectin, galactoside-binding, soluble, 4

Synonyms

GAL4; L36LBP;

Species

Homo sapiens

Ensembl Protein

ENSP00000302100

InnateDB Gene

IDBG-49542 (LGALS4)

Protein Structure

UniProt Annotation

Function

Galectin that binds lactose and a related range of sugars. May be involved in the assembly of adherens junctions.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0030246	carbohydrate binding

Biological Process

GO:0007155	cell adhesion
GO:0045087	innate immune response (InnateDB)

Cellular Component

GO:0005829	cytosol
GO:0005886	plasma membrane

Protein Structure and Domains

PDB ID

InterPro

IPR001079 Galectin, carbohydrate recognition domain
IPR008985 Concanavalin A-like lectin/glucanases superfamily

PFAM

PF00337

PRINTS

PIRSF

SMART

SM00276
SM00908

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P56470

PhosphoSite

PhosphoSite-P56470

TrEMBL

Q6FHZ4

UniProt Splice Variant

Entrez Gene

3960

UniGene

Hs.5302

RefSeq

NP_006140

HUGO

HGNC:6565

OMIM

602518

CCDS

CCDS12521

HPRD

03949

IMGT

EMBL

AB006781 AC022144 AC104534 AF014838 AK290269 BC003661 BC005146 BC034750 BT007032 CH471126 CR536544 U82953

GenPept

AAB86590 AAC51763 AAH03661 AAH05146 AAH34750 AAP35679 BAA22165 BAF82958 CAG38781 EAW56819