InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GPCPD1

Summary

InnateDB Protein

IDBP-51599.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GPCPD1

Protein Name

glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000368305

InnateDB Gene

IDBG-51597 (GPCPD1)

Protein Structure

UniProt Annotation

Function

May be involved in the negative regulation of skeletal muscle differentiation, independently of its glycerophosphocholine phosphodiesterase activity. {ECO:0000250}.

Subcellular Localization

Cytoplasm, cytosol {ECO:0000250}.

Disease Associations

Tissue Specificity

Widely expressed, with highest expression in spinal chord.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008081	phosphoric diester hydrolase activity
GO:0008889	glycerophosphodiester phosphodiesterase activity
GO:0030246	carbohydrate binding
GO:0047389	glycerophosphocholine phosphodiesterase activity
GO:2001070	starch binding

Biological Process

GO:0006071	glycerol metabolic process
GO:0006629	lipid metabolic process
GO:0006644	phospholipid metabolic process
GO:0044281	small molecule metabolic process
GO:0046474	glycerophospholipid biosynthetic process

Cellular Component

GO:0005829

cytosol

Protein Structure and Domains

PDB ID

InterPro

IPR002044 Carbohydrate binding module family 20
IPR013784 Carbohydrate-binding-like fold
IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain

PFAM

PF00686

PRINTS

PIRSF

SMART

SM01065

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9NPB8