InnateDB Protein
|
IDBP-51829.5
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
CHGB
|
Protein Name
|
chromogranin B (secretogranin 1)
|
Synonyms
|
SCG1;
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000368244
|
InnateDB Gene
|
IDBG-51827 (CHGB)
|
Protein Structure
|
|
Function |
Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides.
|
Subcellular Localization |
Secreted. Note=Neuroendocrine and endocrine secretory granules.
|
Disease Associations |
|
Tissue Specificity |
Expressed in the adrenal medulla, and in pheochromocytoma. Not expressed in liver. {ECO:0000269PubMed:3608978}.
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 40 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
40
[view]
|
Protein-Protein |
40
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
Predicted by orthology |
Total |
1 [view]
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR001819
Chromogranin A/B
IPR001990
Chromogranin/secretogranin
|
PFAM |
PF01271
|
PRINTS |
PR00659
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
P05060
|
PhosphoSite |
PhosphoSite-P05060
|
TrEMBL |
|
UniProt Splice Variant |
|
Entrez Gene |
1114
|
UniGene |
Hs.629339
|
RefSeq |
NP_001810
|
HUGO |
HGNC:1930
|
OMIM |
118920
|
CCDS |
CCDS13092
|
HPRD |
07512
|
IMGT |
|
EMBL |
AB209712
AK289386
AL035461
BC000375
CH471133
CR456726
Y00064
|
GenPept |
AAH00375
BAD92949
BAF82075
CAA68271
CAB55272
CAC34360
CAG33007
EAX10410
|
|
|