Version 5.4
Mus musculus Protein: Atm
Summary
InnateDB Protein IDBP-532202.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Atm
Protein Name ataxia telangiectasia mutated homolog (human)
Synonyms AI256621; C030026E19Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000115394
InnateDB Gene IDBG-165511 (Atm)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 120 interaction(s) predicted by orthology.
Experimentally validated
Total 19 [view]
Protein-Protein 18 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 120 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
Biological Process
GO:0000077 DNA damage checkpoint
GO:0000723 telomere maintenance
GO:0001756 somitogenesis
GO:0006281 DNA repair
GO:0006468 protein phosphorylation
GO:0006974 cellular response to DNA damage stimulus
GO:0007292 female gamete generation
GO:0007420 brain development
GO:0007507 heart development
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
GO:0010212 response to ionizing radiation
GO:0016572 histone phosphorylation
GO:0042159 lipoprotein catabolic process
GO:0043525 positive regulation of neuron apoptotic process
GO:0048599 oocyte development
GO:0051402 neuron apoptotic process
GO:0090399 replicative senescence
Cellular Component
GO:0005634 nucleus
GO:0005819 spindle
Protein Structure and Domains
PDB ID MGI:107202
InterPro IPR021668 Telomere-length maintenance and DNA damage repair
PFAM PF11640
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D3Z0Q2
UniProt Splice Variant
Entrez Gene 11920
UniGene Mm.5088
RefSeq
MGI ID
MGI Symbol Atm
OMIM
CCDS
HPRD
IMGT
EMBL AC079869 AC156640
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca