Version 5.4
Mus musculus Protein: Eif2a
Summary
InnateDB Protein IDBP-533040.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Eif2a
Protein Name eukaryotic translation initiation factor 2A
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000120901
InnateDB Gene IDBG-146374 (Eif2a)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000049 tRNA binding
GO:0003743 translation initiation factor activity
GO:0005515 protein binding
GO:0043022 ribosome binding
Biological Process
GO:0006412 translation
GO:0006413 translational initiation
GO:0006417 regulation of translation
GO:0006468 protein phosphorylation
GO:0009967 positive regulation of signal transduction
GO:0032933 SREBP signaling pathway
GO:0042255 ribosome assembly
Cellular Component
GO:0005850 eukaryotic translation initiation factor 2 complex
Protein Structure and Domains
PDB ID MGI:1098684
InterPro IPR013979 Translation initiation factor, beta propellor-like domain
IPR017986 WD40-repeat-containing domain
PFAM PF08662
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D3YZZ6
UniProt Splice Variant
Entrez Gene 229317
UniGene Mm.471324
RefSeq
MGI ID
MGI Symbol Eif2a
OMIM
CCDS
HPRD
IMGT
EMBL AC119873 AC121794
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca