InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Atp6v0c

Summary

InnateDB Protein

IDBP-533278.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Atp6v0c

Protein Name

ATPase, H+ transporting, lysosomal V0 subunit C

Synonyms

Atp6c; Atp6c2; Atp6l; Atpl; Atpl-rs1; PL16; VATL; Vma3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000121464

InnateDB Gene

IDBG-145384 (Atp6v0c)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism
GO:0015078	hydrogen ion transmembrane transporter activity
GO:0031625	ubiquitin protein ligase binding

Biological Process

GO:0007035	vacuolar acidification
GO:0007042	lysosomal lumen acidification
GO:0015991	ATP hydrolysis coupled proton transport

Cellular Component

GO:0005765	lysosomal membrane
GO:0016021	integral component of membrane
GO:0016471	vacuolar proton-transporting V-type ATPase complex
GO:0033177	proton-transporting two-sector ATPase complex, proton-transporting domain
GO:0033179	proton-transporting V-type ATPase, V0 domain

Protein Structure and Domains

PDB ID

MGI:88116

InterPro

IPR000245 V-ATPase proteolipid subunit
IPR002379 V-ATPase proteolipid subunit C-like domain
IPR011555 V-ATPase proteolipid subunit C, eukaryotic

PFAM

PF00137

PRINTS

PR00122

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E9Q9C5

UniProt Splice Variant

Entrez Gene

11984

UniGene

Mm.449294

RefSeq

MGI ID

MGI Symbol

Atp6v0c

OMIM

CCDS

HPRD

IMGT

EMBL

CT010502

GenPept