InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Eps8

Summary

InnateDB Protein

IDBP-534623.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Eps8

Protein Name

epidermal growth factor receptor pathway substrate 8

Synonyms

AW261790;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000119997

InnateDB Gene

IDBG-195386 (Eps8)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
They are also associated with 47 interaction(s) predicted by orthology.

Experimentally validated
Total	23 [view]
Protein-Protein	23 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	47 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0008344	adult locomotory behavior
GO:0031532	actin cytoskeleton reorganization
GO:0045087	innate immune response (InnateDB)
GO:0048149	behavioral response to ethanol
GO:0051017	actin filament bundle assembly

Cellular Component

GO:0014069	postsynaptic density
GO:0017146	N-methyl-D-aspartate selective glutamate receptor complex
GO:0045202	synapse
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:104684

InterPro

IPR006020 PTB/PI domain
IPR013625 Tensin phosphotyrosine-binding domain

PFAM

PF00640
PF14719
PF08416

PRINTS

PIRSF

SMART

SM00462

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3Z7F4

UniProt Splice Variant

Entrez Gene

13860

UniGene

Mm.488641

RefSeq

MGI ID

MGI Symbol

Eps8

OMIM

CCDS

HPRD

IMGT

EMBL

AC093120 AC166347

GenPept