Version 5.4
Homo sapiens Protein: B3GNT2
Summary
InnateDB Protein IDBP-53477.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol B3GNT2
Protein Name UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
Synonyms B3GN-T2; B3GNT; B3GNT-2; B3GNT1; BETA3GNT; BGnT-2; BGNT2;
Species Homo sapiens
Ensembl Protein ENSP00000305595
InnateDB Gene IDBG-53475 (B3GNT2)
Protein Structure
UniProt Annotation
Function Catalyzes the initiation and elongation of poly-N- acetyllactosamine chains. {ECO:0000269PubMed:9892646}.
Subcellular Localization Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Ubiquitous. {ECO:0000269PubMed:11042166}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008378 galactosyltransferase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006486 protein glycosylation
GO:0007411 axon guidance
GO:0007608 sensory perception of smell
GO:0008150 biological_process
GO:0016266 O-glycan processing
GO:0018146 keratan sulfate biosynthetic process
GO:0030203 glycosaminoglycan metabolic process
GO:0042339 keratan sulfate metabolic process
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0000139 Golgi membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR002659 Glycosyl transferase, family 31
PFAM PF01762
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NY97
PhosphoSite PhosphoSite-Q9NY97
TrEMBL
UniProt Splice Variant
Entrez Gene 10678
UniGene Hs.644986
RefSeq NP_006568
HUGO HGNC:15629
OMIM 605581
CCDS CCDS1870
HPRD 09279
IMGT
EMBL AB049584 AC093401 AF092051 AF288208 AF288209 AJ006077 AK002009 BC030579 BC047933 CH471053
GenPept AAD09764 AAF97253 AAF97254 AAH30579 AAH47933 AAX93271 BAA92031 BAB21530 CAB91546 EAW99977 EAW99978 EAW99979

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca