Mus musculus Protein: Mkl2
Summary
InnateDB Protein IDBP-535870.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mkl2
Protein Name MKL/myocardin-like 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000122815
InnateDB Gene IDBG-133693 (Mkl2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003779 actin binding
GO:0005515 protein binding
Biological Process
GO:0001701 in utero embryonic development
GO:0001889 liver development
GO:0003007 heart morphogenesis
GO:0007507 heart development
GO:0010467 gene expression
GO:0010468 regulation of gene expression
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048514 blood vessel morphogenesis
GO:0048568 embryonic organ development
GO:0048738 cardiac muscle tissue development
GO:0051145 smooth muscle cell differentiation
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:3050795
InterPro IPR003034 SAP domain
IPR004018 RPEL repeat
PFAM PF02037
PF02755
PRINTS
PIRSF
SMART SM00513
SM00707
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q5DTZ3
UniProt Splice Variant
Entrez Gene 239719
UniGene Mm.270643
RefSeq NP_705816
MGI ID
MGI Symbol Mkl2
OMIM
CCDS CCDS37258
HPRD
IMGT
EMBL AC160961 AC163640 AK220377 BC131644
GenPept AAI31645 BAD90435