InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Vrk2

Summary

InnateDB Protein

IDBP-536494.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Vrk2

Protein Name

vaccinia related kinase 2

Synonyms

2810003O05Rik; AI447698;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000119928

InnateDB Gene

IDBG-156163 (Vrk2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	15 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004674	protein serine/threonine kinase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0006468	protein phosphorylation
GO:0034599	cellular response to oxidative stress
GO:0043408	regulation of MAPK cascade
GO:0046777	protein autophosphorylation
GO:2000659	regulation of interleukin-1-mediated signaling pathway

Cellular Component

GO:0005634	nucleus
GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0016020	membrane
GO:0031966	mitochondrial membrane

Protein Structure and Domains

PDB ID

MGI:1917172

InterPro

IPR011009 Protein kinase-like domain

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q5SP86

UniProt Splice Variant

Entrez Gene

69922

UniGene

Mm.285351

RefSeq

MGI ID

MGI Symbol

Vrk2

OMIM

CCDS

HPRD

IMGT

EMBL

AC083815 AL929272

GenPept