InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mfn1

Summary

InnateDB Protein

IDBP-536956.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mfn1

Protein Name

mitofusin 1

Synonyms

2310002F04Rik; 6330416C07Rik; D3Ertd265e; HR2; mKIAA4032;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000117411

InnateDB Gene

IDBG-136722 (Mfn1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	11 [view]
Protein-Protein	11 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0005515	protein binding
GO:0005525	GTP binding

Biological Process

GO:0006184	GTP catabolic process
GO:0008053	mitochondrial fusion
GO:0045087	innate immune response (InnateDB)

Cellular Component

GO:0005739	mitochondrion
GO:0005741	mitochondrial outer membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1914664

InterPro

IPR001401 Dynamin, GTPase domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00350

PRINTS

PIRSF

SMART

SM00053

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3Z4L5

UniProt Splice Variant

Entrez Gene

67414

UniGene

Mm.290414

RefSeq

MGI ID

MGI Symbol

Mfn1

OMIM

CCDS

HPRD

IMGT

EMBL

AC130281

GenPept