Version 5.4
Homo sapiens Protein: AFTPH
Summary
InnateDB Protein IDBP-53952.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AFTPH
Protein Name aftiphilin
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000238855
InnateDB Gene IDBG-53948 (AFTPH)
Protein Structure
UniProt Annotation
Function May play a role in membrane trafficking.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:14665628}. Note=Colocalizes with AP1G1 and clathrin.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 6 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0030276 clathrin binding
Biological Process
GO:0015031 protein transport
Cellular Component
GO:0005829 cytosol
GO:0030121 AP-1 adaptor complex
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6ULP2
PhosphoSite PhosphoSite-Q6ULP2
TrEMBL
UniProt Splice Variant
Entrez Gene 54812
UniGene Hs.713206
RefSeq NP_982261
HUGO HGNC:25951
OMIM
CCDS CCDS46303
HPRD 10635
IMGT
EMBL AK000087 AK021899 AK024658 AL833962 AY367088 BC022247 BC047529 CH471053
GenPept AAH22247 AAH47529 AAR14726 BAA90936 BAB13930 BAB14949 CAE46209 EAW99938 EAW99941

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca