InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Dhcr7

Summary

InnateDB Protein

IDBP-539894.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Dhcr7

Protein Name

7-dehydrocholesterol reductase

Synonyms

AA409147;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000121782

InnateDB Gene

IDBG-212845 (Dhcr7)

Protein Structure

UniProt Annotation

Function

Production of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC).

Subcellular Localization

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0047598	7-dehydrocholesterol reductase activity

Biological Process

GO:0001568	blood vessel development
GO:0006695	cholesterol biosynthetic process
GO:0009791	post-embryonic development
GO:0016126	sterol biosynthetic process
GO:0030154	cell differentiation
GO:0030324	lung development
GO:0035264	multicellular organism growth
GO:0042127	regulation of cell proliferation
GO:0045540	regulation of cholesterol biosynthetic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005640	nuclear outer membrane
GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0016020	membrane
GO:0016021	integral component of membrane