InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pias3

Summary

InnateDB Protein

IDBP-542552.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pias3

Protein Name

protein inhibitor of activated STAT 3

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000125377

InnateDB Gene

IDBG-176105 (Pias3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 47 interaction(s) predicted by orthology.

Experimentally validated
Total	18 [view]
Protein-Protein	17 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	47 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0005515	protein binding
GO:0008022	protein C-terminus binding
GO:0015459	potassium channel regulator activity
GO:0019789	SUMO ligase activity
GO:0019899	enzyme binding
GO:0047485	protein N-terminus binding

Biological Process

GO:0009725	response to hormone
GO:0010628	positive regulation of gene expression
GO:0016925	protein sumoylation
GO:0033235	positive regulation of protein sumoylation
GO:0045838	positive regulation of membrane potential

Cellular Component

GO:0005634	nucleus
GO:0030425	dendrite
GO:0045202	synapse

Protein Structure and Domains

PDB ID

MGI:1913126

InterPro

IPR003034 SAP domain

PFAM

PF02037

PRINTS

PIRSF

SMART

SM00513

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E0CZH5

UniProt Splice Variant

Entrez Gene

229615

UniGene

RefSeq

MGI ID

MGI Symbol

Pias3

OMIM

CCDS

HPRD

IMGT

EMBL

AC112261

GenPept