InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Adam10

Summary

InnateDB Protein

IDBP-542647.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Adam10

Protein Name

a disintegrin and metallopeptidase domain 10

Synonyms

1700031C13Rik; kuz; kuzbanian; MADM;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000116867

InnateDB Gene

IDBG-182594 (Adam10)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Experimentally validated
Total	10 [view]
Protein-Protein	9 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004175	endopeptidase activity
GO:0004222	metalloendopeptidase activity
GO:0005515	protein binding

Biological Process

GO:0006509	membrane protein ectodomain proteolysis
GO:0007219	Notch signaling pathway

Cellular Component

GO:0014069

postsynaptic density

Protein Structure and Domains

PDB ID

MGI:109548

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3Z1E6

UniProt Splice Variant

Entrez Gene

11487

UniGene

Mm.473247

RefSeq

MGI ID

MGI Symbol

Adam10

OMIM

CCDS

HPRD

IMGT

EMBL

AC091263 AC160636 CT025701

GenPept