InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Stx1a

Summary

InnateDB Protein

IDBP-542754.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Stx1a

Protein Name

syntaxin 1A (brain)

Synonyms

HPC-1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000117144

InnateDB Gene

IDBG-203389 (Stx1a)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 41 experimentally validated interaction(s) in this database.
They are also associated with 37 interaction(s) predicted by orthology.

Experimentally validated
Total	41 [view]
Protein-Protein	41 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	37 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000149	SNARE binding
GO:0001948	glycoprotein binding
GO:0005515	protein binding
GO:0019855	calcium channel inhibitor activity

Biological Process

GO:0016192	vesicle-mediated transport
GO:0017156	calcium ion-dependent exocytosis
GO:0017157	regulation of exocytosis

Cellular Component

GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030672	synaptic vesicle membrane
GO:0043005	neuron projection
GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex
GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex

Protein Structure and Domains

PDB ID

MGI:109355

InterPro

IPR000727 Target SNARE coiled-coil domain
IPR006011 Syntaxin, N-terminal domain
IPR010989 t-SNARE

PFAM

PF05739
PF00804

PRINTS

PIRSF

SMART

SM00397
SM00503

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D6RFB9

UniProt Splice Variant

Entrez Gene

20907

UniGene

Mm.6225

RefSeq

MGI ID

MGI Symbol

Stx1a

OMIM

CCDS

HPRD

IMGT

EMBL

AC084109

GenPept