InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RRBP1

Summary

InnateDB Protein

IDBP-56145.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RRBP1

Protein Name

ribosome binding protein 1 homolog 180kDa (dog)

Synonyms

ES/130; ES130; hES; RRp;

Species

Homo sapiens

Ensembl Protein

ENSP00000246043

InnateDB Gene

IDBG-56137 (RRBP1)

Protein Structure

UniProt Annotation

Function

Acts as a ribosome receptor and mediates interaction between the ribosome and the endoplasmic reticulum membrane. {ECO:0000250}.

Subcellular Localization

Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 38 experimentally validated interaction(s) in this database.

Experimentally validated
Total	38 [view]
Protein-Protein	38 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004872	receptor activity
GO:0044822	poly(A) RNA binding

Biological Process

GO:0001649	osteoblast differentiation
GO:0006412	translation
GO:0015031	protein transport

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0005840	ribosome
GO:0016020	membrane
GO:0030176	integral component of endoplasmic reticulum membrane

Protein Structure and Domains

PDB ID

InterPro

IPR007794 Ribosome receptor lysine/proline rich
IPR023584 Ribosome recycling factor domain

PFAM

PF05104
PF01765

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9P2E9

PhosphoSite

PhosphoSite-Q9P2E9

TrEMBL

F8W7S5

UniProt Splice Variant

Entrez Gene

6238

UniGene

Hs.706335

RefSeq

HUGO

HGNC:10448

OMIM

601418

CCDS

HPRD

11796

IMGT

EMBL

AB037819 AF006751 AF007575 AL132765 AL833822 BC000099

GenPept

AAC25977 AAC25978 AAH00099 BAA92636 CAC10587 CAD38684 CAH74034