Version 5.4
Homo sapiens Protein: ZFPL1
Summary
InnateDB Protein IDBP-56387.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZFPL1
Protein Name zinc finger protein-like 1
Synonyms D11S750; MCG4;
Species Homo sapiens
Ensembl Protein ENSP00000294258
InnateDB Gene IDBG-56385 (ZFPL1)
Protein Structure
UniProt Annotation
Function Required for cis-Golgi integrity and efficient ER to Golgi transport. Involved in the maintenance of the integrity of the cis-Golgi, possibly via its interaction with GOLGA2/GM130. {ECO:0000269PubMed:18323775}.
Subcellular Localization Golgi apparatus, cis-Golgi network membrane {ECO:0000269PubMed:18323775}; Single-pass membrane protein {ECO:0000269PubMed:18323775}.
Disease Associations
Tissue Specificity Expressed strongly in the exocrine pancreas. {ECO:0000269PubMed:9653652}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0005634 nucleus
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O95159
PhosphoSite PhosphoSite-O95159
TrEMBL E9PQ47
UniProt Splice Variant
Entrez Gene 7542
UniGene
RefSeq NP_006773
HUGO HGNC:12868
OMIM
CCDS CCDS8092
HPRD 15729
IMGT
EMBL AF001891 AF030291 AF043611 AK291964 AP003068 BC012530 BC012814 CH471076
GenPept AAB86533 AAD08644 AAF21634 AAH12530 AAH12814 BAF84653 EAW74344 EAW74346

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca