InnateDB Protein
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IDBP-56517.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CCNG1
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Protein Name
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cyclin G1
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Synonyms
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CCNG;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000344635
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InnateDB Gene
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IDBG-56515 (CCNG1)
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Protein Structure
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Function |
May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation (By similarity). {ECO:0000250}.
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Subcellular Localization |
Nucleus {ECO:0000269PubMed:10196184}. Note=DNA replication foci after DNA damage.
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Disease Associations |
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Tissue Specificity |
High levels in skeletal muscle, ovary, kidney and colon.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated |
Total |
24
[view]
|
Protein-Protein |
23
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
4 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR006671
Cyclin, N-terminal
IPR013763
Cyclin-like
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PFAM |
PF00134
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PRINTS |
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PIRSF |
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SMART |
SM00385
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TIGRFAMs |
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Modification |
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SwissProt |
P51959
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PhosphoSite |
PhosphoSite-P51959
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TrEMBL |
D6RGX3
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UniProt Splice Variant |
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Entrez Gene |
900
|
UniGene |
Hs.79101
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RefSeq |
NP_004051
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HUGO |
HGNC:1592
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OMIM |
601578
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CCDS |
CCDS4360
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HPRD |
03345
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IMGT |
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EMBL |
AC112205
AK297190
AK312913
AK316234
AY791292
BC000196
BC007093
BT007134
CH471062
D78341
D86077
L49504
U47413
U53328
X77794
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GenPept |
AAB03903
AAC41977
AAC50688
AAH00196
AAH07093
AAP35798
AAV40836
BAA11353
BAA13007
BAG35759
BAG59679
BAH14605
CAA54821
EAW61528
EAW61529
EAW61530
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