InnateDB Protein
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IDBP-57302.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CKM
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Protein Name
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creatine kinase, muscle
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Synonyms
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CKMM; M-CK;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000221476
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InnateDB Gene
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IDBG-57300 (CKM)
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Protein Structure
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Function |
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
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Subcellular Localization |
Cytoplasm.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated |
Total |
13
[view]
|
Protein-Protein |
13
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
5 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR022413
ATP:guanido phosphotransferase, N-terminal
IPR022414
ATP:guanido phosphotransferase, catalytic domain
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PFAM |
PF02807
PF00217
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P06732
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PhosphoSite |
PhosphoSite-P06732
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
1158
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UniGene |
Hs.742410
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RefSeq |
NP_001815
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HUGO |
HGNC:1994
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OMIM |
123310
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CCDS |
CCDS12659
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HPRD |
00426
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IMGT |
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EMBL |
AC005781
AY585238
BC007462
BT006793
M14780
M16440
M21488
M21489
M21490
M21491
M21492
M21493
M21494
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GenPept |
AAA52025
AAA52026
AAA96609
AAC62841
AAH07462
AAP35439
AAS79321
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