InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: FOSL1

Summary

InnateDB Protein

IDBP-58046.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FOSL1

Protein Name

FOS-like antigen 1

Synonyms

FRA; fra-1; FRA1;

Species

Homo sapiens

Ensembl Protein

ENSP00000310170

InnateDB Gene

IDBG-58044 (FOSL1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 51 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0001701	in utero embryonic development
GO:0006355	regulation of transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006366	transcription from RNA polymerase II promoter
GO:0006935	chemotaxis
GO:0006968	cellular defense response
GO:0007296	vitellogenesis
GO:0007565	female pregnancy
GO:0007612	learning
GO:0008284	positive regulation of cell proliferation
GO:0008285	negative regulation of cell proliferation
GO:0009612	response to mechanical stimulus
GO:0009615	response to virus
GO:0009629	response to gravity
GO:0014070	response to organic cyclic compound
GO:0031668	cellular response to extracellular stimulus
GO:0032570	response to progesterone
GO:0034097	response to cytokine
GO:0042493	response to drug
GO:0042542	response to hydrogen peroxide
GO:0043065	positive regulation of apoptotic process
GO:0045787	positive regulation of cell cycle
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051412	response to corticosterone
GO:0051591	response to cAMP
GO:0060674	placenta blood vessel development