Version 5.4
Homo sapiens Protein: GRASP
Summary
InnateDB Protein IDBP-583413.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GRASP
Protein Name GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000449492
InnateDB Gene IDBG-33946 (GRASP)
Protein Structure
UniProt Annotation
Function Plays a role in intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses. {ECO:0000250}.
Subcellular Localization Cytoplasm, perinuclear region {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}. Note=Localized at postsynaptic membranes. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0030054 cell junction
GO:0045211 postsynaptic membrane
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR001478 PDZ domain
PFAM PF00595
PF13180
PRINTS
PIRSF
SMART SM00228
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7Z6J2
PhosphoSite PhosphoSite-Q7Z6J2
TrEMBL
UniProt Splice Variant
Entrez Gene 160622
UniGene Hs.407202
RefSeq NP_001258785
HUGO HGNC:18707
OMIM 612027
CCDS CCDS61124
HPRD 17077
IMGT
EMBL BC035500 BC052967 BC053666
GenPept AAH35500 AAH52967 AAH53666

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca