InnateDB Protein
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IDBP-583523.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SYT12
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Protein Name
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synaptotagmin XII
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000435316
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InnateDB Gene
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IDBG-59801 (SYT12)
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Protein Structure
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Function |
May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. {ECO:0000250}.
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Subcellular Localization |
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000008
C2 domain
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PFAM |
PF00168
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PRINTS |
PR00360
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PIRSF |
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SMART |
SM00239
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TIGRFAMs |
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Modification |
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SwissProt |
Q8IV01
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PhosphoSite |
PhosphoSite-Q8IV01
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TrEMBL |
Q8NDM9
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UniProt Splice Variant |
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Entrez Gene |
91683
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UniGene |
Hs.287636
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RefSeq |
NP_808878
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HUGO |
HGNC:18381
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OMIM |
606436
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CCDS |
CCDS8154
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HPRD |
07337
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IMGT |
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EMBL |
AL833834
AP000729
AP003176
BC037406
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GenPept |
AAH37406
CAD38694
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