InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RAB18

Summary

InnateDB Protein

IDBP-583663.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RAB18

Protein Name

RAB18, member RAS oncogene family

Synonyms

RAB18LI1; WARBM3;

Species

Homo sapiens

Ensembl Protein

ENSP00000439321

InnateDB Gene

IDBG-64998 (RAB18)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.

Experimentally validated
Total	7 [view]
Protein-Protein	6 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0005515	protein binding
GO:0005525	GTP binding
GO:0019003	GDP binding

Biological Process

GO:0001654	eye development
GO:0006184	GTP catabolic process
GO:0007165	signal transduction
GO:0007264	small GTPase mediated signal transduction
GO:0007420	brain development
GO:0015031	protein transport
GO:0034389	lipid particle organization

Cellular Component

GO:0005622	intracellular
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR001806 Small GTPase superfamily
IPR003579 Small GTPase superfamily, Rab type
IPR013684 Mitochondrial Rho-like
IPR020849 Small GTPase superfamily, Ras type
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00071
PF08477

PRINTS

PR00449

PIRSF

SMART

SM00175
SM00173

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt