Version 5.4
Homo sapiens Protein: ATM
Summary
InnateDB Protein IDBP-584640.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ATM
Protein Name ataxia telangiectasia mutated
Synonyms AT1; ATA; ATC; ATD; ATDC; ATE; TEL1; TELO1;
Species Homo sapiens
Ensembl Protein ENSP00000434327
InnateDB Gene IDBG-70193 (ATM)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 221 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 221 [view]
Protein-Protein 210 [view]
Protein-DNA 8 [view]
Protein-RNA 1 [view]
DNA-DNA 2 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004674 protein serine/threonine kinase activity
Biological Process
GO:0000077 DNA damage checkpoint
GO:0000723 telomere maintenance
GO:0006281 DNA repair
GO:0010212 response to ionizing radiation
GO:0016572 histone phosphorylation
GO:0090399 replicative senescence
Cellular Component
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H0YDU7
UniProt Splice Variant
Entrez Gene 472
UniGene Hs.710771
RefSeq
HUGO HGNC:795
OMIM 607585
CCDS
HPRD 06347
IMGT
EMBL AP001925 AP005718
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca