Version 5.4
Homo sapiens Protein: TNFRSF1A
Summary
InnateDB Protein IDBP-584726.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TNFRSF1A
Protein Name tumor necrosis factor receptor superfamily, member 1A
Synonyms CD120a; FPF; MS5; p55; p55-R; p60; TBP1; TNF-R; TNF-R-I; TNF-R55; TNFAR; TNFR1; TNFR1-d2; TNFR55; TNFR60;
Species Homo sapiens
Ensembl Protein ENSP00000438343
InnateDB Gene IDBG-13807 (TNFRSF1A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 168 experimentally validated interaction(s) in this database.
They are also associated with 30 interaction(s) predicted by orthology.
Experimentally validated
Total 168 [view]
Protein-Protein 165 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 30 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
GO:0045087 innate immune response (InnateDB)
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000488 Death domain
IPR001368 TNFR/NGFR cysteine-rich region
IPR011029 Death-like domain
PFAM PF00531
PF00020
PRINTS
PIRSF
SMART SM00005
SM00208
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL J9PH39
UniProt Splice Variant
Entrez Gene 7132
UniGene Hs.279594
RefSeq
HUGO HGNC:11916
OMIM 191190
CCDS
HPRD 01861
IMGT
EMBL AC006057 JN172914
GenPept AEO89726

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca