InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: F7

Summary

InnateDB Protein

IDBP-585494.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Protein Name

coagulation factor VII (serum prothrombin conversion accelerator)

Synonyms

SPCA;

Species

Homo sapiens

Ensembl Protein

ENSP00000442051

InnateDB Gene

IDBG-52192 (F7)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.

Experimentally validated
Total	15 [view]
Protein-Protein	14 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004252	serine-type endopeptidase activity
GO:0005509	calcium ion binding
GO:0005515	protein binding

Biological Process

GO:0006508	proteolysis
GO:0007596	blood coagulation

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000742 Epidermal growth factor-like domain
IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR001881 EGF-like calcium-binding domain
IPR009003 Trypsin-like cysteine/serine peptidase domain
IPR012224 Peptidase S1A, coagulation factor VII/IX/X/C/Z
IPR015420 Peptidase S1A, nudel

PFAM

PF00008
PF00089
PF07645
PF09342

PRINTS

PR00722

PIRSF

PIRSF001143

SMART

SM00181
SM00020
SM00179

TIGRFAMs

Post-translational Modifications

Modification

Cross-References