InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HDAC4

Summary

InnateDB Protein

IDBP-585555.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HDAC4

Protein Name

histone deacetylase 4

Synonyms

AHO3; BDMR; HA6116; HD4; HDAC-4; HDAC-A; HDACA;

Species

Homo sapiens

Ensembl Protein

ENSP00000440481

InnateDB Gene

IDBG-84594 (HDAC4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 253 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.

Experimentally validated
Total	253 [view]
Protein-Protein	182 [view]
Protein-DNA	4 [view]
Protein-RNA	0
DNA-DNA	67 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	21 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004407	histone deacetylase activity

Biological Process

GO:0016568

chromatin modification

Cellular Component

GO:0000118

histone deacetylase complex

Protein Structure and Domains

PDB ID

InterPro

IPR000286 Histone deacetylase superfamily
IPR017320 Histone deacetylase class II, eukaryotic
IPR019154 Arb2 domain
IPR023801 Histone deacetylase domain
IPR024643 Histone deacetylase, glutamine rich N-terminal domain

PFAM

PF09757
PF00850
PF12203

PRINTS

PR01270

PIRSF

PIRSF037911

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt